¹⁸F-FDG PET/CT for Identifying the Potential Primary Diseases and Predicting Prognosis of Secondary Hemophagocytic Lymphohistiocytosis in Children

Table 3

Comparison of focal hypermetabolism between M-HLH and NM-HLH group.

Organ with focal metabolic hypermetabolism	M-HLH (n = 13)		NM-HLH (n = 49)		x^2	value
	Yes	No	Yes	No
Lymph nodes	11	2	41	8	<0.001	<1.000
Extranodal organs	9	4	15	34	6.458	0.011
Spleen	1	12	6	43	<0.001	<1.000
Liver	2	11	3	46	—	0.280
Bone marrow	5	8	6	43	3.209	0.073
Intracranial	2	11	2	47	—	0.191
Lung	3	10	2	47	—	0.058
Intestinal	2	11	0	49	—	0.041
Renal	2	11	4	45	—	0.597
Adrenal	1	12	1	48	—	0.378
Skin and/or nasal mucosa	4	9	3	46	4.014	0.045
Central nervous system	1	12	1	48	—	0.378
Muscle	0	13	2	47	—	<1.000

M-HLH: malignancy-associated HLH and NM-HLH: non-malignancy-associated HLH.