Mechanism of Jujube (Ziziphus jujuba Mill.) Fruit in the Appetite Regulation Based on Network Pharmacology and Molecular Docking Method

Table 2

cytoHubba five-algorithm calculation results ranking.

Rank	MCC	CLONESS	MNC	EPC	DEGREE
1	MAOA	MAPK3	MAPK3	MAPK3	MAPK3
2	DRD2	EGFR	EGFR	SRC	EGFR
3	HTR1A	SRC	SRC	EGFR	SRC
4	DRD4	HSP90AA1	HSP90AA1	APP	HSP90AA1
5	DRD3	ESR1	TNF	HSP90AA1	TNF
6	SLC6A3	TNF	ESR1	ESR1	ESR1
7	SLC18A2	APP	APP	PIK3CA	APP
8	ADRA2C	PIK3CA	PIK3CA	TNF	PIK3CA
9	ADRA2A	BRCA1	BRCA1	RELA	BRCA1
10	HTR3A	RELA	GRIN2B	BRCA1	GRIN2B
11	HTR1B	GSK3B	SLC6A3	GSK3B	SLC6A3
12	CHRNA4	GRIN2B	HTR3A	GRIN2B	HTR3A
13	ACHE	MAPT	RELA	NTRK2	RELA
14	PIK3CA	PRKCA	CHRNA4	NFKB1	CHRNA4
15	HTR2A	PPARG	ACHE	CHRNA4	ACHE
16	ADRA1B	NTRK2	CDK1	DRD2	GSK3B
17	ADRA1A	NFKB1	DRD2	SLC6A3	CDK1
18	ADRA1D	CDK1	MAOA	PRKCA	DRD2
19	HTR2C	DRD2	NTRK2	ACHE	MAOA
20	HTR2B	ACHE	GSK3B	MAPT	PPARG
21	APP	HIF1A	PPARG	IGF1R	NTRK2
22	OXTR	CHRNA4	HIF1A	CDK1	HIF1A
23	F2	CDK5	MAPT	HIF1A	SLC18A2
24	NTSR1	GRIN1	MMP2	HTR3A	GRIN1
25	SRC	IGF1R	TOP2A	SLC18A2	MAPT
26	EGFR	ABCB1	NFKB1	PPARG	MMP2
27	MAPK3	PTPN1	SLC18A2	ADRA1B	TOP2A
28	HSP90AA1	MMP2	GRIN1	MAOA	NFKB1
29	ESR1	TOP2A	PRKCA	MCL1	PRKCA
30	RELA	F2	DRD4	GRIN1	DRD4