Identification of Hub Genes and Key Pathways Associated with Follicular Lymphoma

Table 2

Considerably enriched KEGG terms of hub genes.

KEGG ID	Term	P value	FDR	Gene
hsa04060	Cytokine-cytokine receptor interaction	3.41E-05	0.001398803	CXCL9, CXCL12, CCL5, IL18, CCL2, CCR5
hsa04062	Chemokine signaling pathway	2.16E-04	0.004430241	CXCL9, CXCL12, CCL5, CCL2, CCR5
hsa05323	Rheumatoid arthritis	4.09E-04	0.005595854	CXCL12, CCL5, IL18, CCL2
hsa04668	TNF signaling pathway	7.27E-04	0.007450133	VCAM1, CCL5, CCL2, MMP9
hsa05144	Malaria	0.003134748	0.025704934	VCAM1, IL18, CCL2
hsa04621	NOD-like receptor signaling pathway	0.004077271	0.027861351	CCL5, IL18, CCL2
hsa04512	ECM-receptor interaction	0.009611516	0.05629602	COL3A1, COL1A2, FN1
hsa05146	Amoebiasis	0.014037109	0.071940185	COL3A1, COL1A2, FN1
hsa04670	Leukocyte transendothelial migration	0.01639082	0.074669289	CXCL12, VCAM1, MMP9
hsa05164	Influenza A	0.035546833	0.145742015	CCL5, IL18, CCL2
hsa04510	Focal adhesion	0.048349706	0.180212542	COL3A1, COL1A2, FN1
hsa05143	African trypanosomiasis	0.056115365	0.191727498	VCAM1, IL18

ECM, extracellular matrix; FDR, false discovery rate; ID, identity document; NOD, nucleotide-binding oligomerization domain; KEGG, Kyoto Encyclopedia of Genes and Genomes; TNF, tumor necrosis factor.