Research Article
Lymph Node Metastases Detection Using Gd2O3@PCD as Novel Multifunctional Contrast Imaging Agent in Metabolic Magnetic Resonance Molecular Imaging
Figure 2
(a) TEM images of Gd2O3@ PCD NPs, TEM images reveal that Gd2O3@PCD NPs are spherical and uniform that could be visualized separately with clear grains in nano dimensions with a range of 20–30 nm. (b) Intensity-based DLS data on same 100 µg/ml dispersion of Gd2O3@PCD (∼45 nm mean size). This result showed that Gd2O3 nanoparticles had a hydrodynamic diameter distribution of 45 ± 7.6 nm with a PDI of 0.36 that is the proper size. (c) Zeta potential of Gd2O3@PCD and Gd2O3NPs. The Zeta potentials value of Gd2O3 and Gd2O3@PCD NPs were (+17.5 mv) and (−37.5 mv), respectively, which confirms adequate chemical surface repulsion potential of Gd2O3 coating with PCD.
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