Research Article

Lymph Node Metastases Detection Using Gd2O3@PCD as Novel Multifunctional Contrast Imaging Agent in Metabolic Magnetic Resonance Molecular Imaging

Figure 4

Histopathology of lymph node tissue and tumor mass. (a) Schematic of lymph nodes in mice with 4T1 tumor. (b) Red arrows and ROI, respectively, axillary LN. (c and d) Black Arrows: Metastatic tumor cells in axillary LN, H&E stain, Magnification: X100-X400. (e, f, and g) Original tumor mass, Mitotic figures, arrowheads: metastatic cells in the blood and lymphatic vessels. Focal metastasis of breast cancer (arrows) was seen in the harvested lymph node.