Research Article

Lymph Node Metastases Detection Using Gd2O3@PCD as Novel Multifunctional Contrast Imaging Agent in Metabolic Magnetic Resonance Molecular Imaging

Figure 5

MR Imaging of tumor in a mouse model with 4T1 carcinoma in the right lower limb. Example of white arrows in the muscle of right femur tumor. (a) Schematic of axillary lymph nodes and injection method in mice. (b and c) MR image before and after injection of Gd2O3@PCD and Dotarem (0.6 mM). Gd2O3-PCD showed higher and more prolonged enhancement in tumors, with the greatest contrast visible at 15 minutes.
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