Review Article

PET/CT Evaluation of the Effect of Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of T-Cell Lymphoblastic Lymphoma

Table 4

Application limitations of 18F-FDG PET/CT.

Reference no.TitleResearch objectiveApplication limitations of 18F-FDG PET/CT

[36]18F-FLT-PET/CT adds value to 18F-FDG-PET/CT for diagnosing relapse after definitive radiotherapy in patients with lung cancer. Results of a prospective clinical trialIt investigated the value of 18F-FLT-PET/CT and 18F-FDG-PET/CT in diagnosing recurrence of radiation cancerThe specificity of 18F-FLT-PET/CT and 18F-FDG-PET/CT in the diagnosis of cancer patients after recurrence was reduced, and the efficiency of single application was significantly lower than the effect of the combination of the two

[37]Prognostic value of 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography after autologous hematopoietic stem cell transplantation in lymphoma using deauville scoresIt aimed to evaluate 2-deoxy-2-[18F]fluoro-D-glucose ([18F]F-FDG) positron emission tomography (PET)/computed tomography (CT) in lymphoma autologous stem cell transplantation (ASCT)Applicable time was limited.

[38]Prognostic value of 18F-FDG PET/CT in T-Lymphoblastic lymphoma before and after hematopoietic stem cell transplantationIt was to evaluate the prognostic value of 18F-FDG PET/CT in patients with relapsed or refractory t-lymphoid transplantation (T-LBL) undergoing hematopoietic stem cell transplantation (HSCT).Pre-PET failed to predict PFS and OS in T-LBL patients treated with HSCT.

[41]Prediction of outcome in pediatric Hodgkin lymphoma based on interpretation of 18FDG-PET/CT according to DSUVmax, deauville 5-point scale and IHP criteriaIt compared different interpretation methods of 18F-FDG PET/CT in predicting disease prognosis to determine the best method in this regardEffective evaluation indicators for predicting disease prognosis were different before and after treatment, and further research was needed to find the best indicator

[42]Performance of advanced imaging modalities at diagnosis and treatment response evaluation of patients with posttransplant lymphoproliferative disorder: a systematic review and meta-analysisIt aimed to evaluate the clinical performance of advanced imaging modalities in the diagnosis and treatment response assessment of PTLD patients after solid organ and hematopoietic stem cell transplantationFDG-PET(/CT) was well-applied for detection, staging, and treatment evaluation, but has methodological flaws, false-negatives due to physiologic high background activity and early PTLD lesions, and false-positives due to inflammatory conditions

[43]Diagnostic performances of F-18 FDG PET or PET/CT for detection of posttransplant lymphoproliferative disorder: a systematic review and meta-analysisIt aimed to investigate the diagnostic performance of F-18 FDG PET or PET or PET/CT for the detection of posttransplant lymphoproliferative disease (PTLD)The scope of the study was limited and further large multicenter studies were needed to confirm