Long Noncoding RNA CASC2 Facilitated Wound Healing through miRNA-155/HIF-1α in Diabetic Foot Ulcers

Figure 2

Increased expression of lncRNA CASC2 contributes to DFU wound healing as follows. (a) RT-qPCR to reveal the level of expression of the lncRNA CASC2 in cells. (b, c) Cytometry of flow to evaluate the apoptosis of fibroblasts. (d) Wound healing assay to determine the change in migration ability of cells. (e) The proliferation activity of fibroblasts was measured by MTT. (f) Images of wound healing on the foot of DFU mice. (g) RT-qPCR to reveal the level of expression of lncRNA CASC2 in DFU mice. (h) Western blot was utilized for the measurement of the HIF-1α’s expression, VEGF, and Col-I in DFU mice. , , and against a group of DFU.

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