Research Article
The Application of [68Ga]-Labeled FAPI-04 PET/CT for Targeting and Early Detection of Pancreatic Carcinoma in Patient-Derived Orthotopic Xenograft Models
Figure 4
Histological and immunohistochemical of PDOX models. (a) Patient-derived tumor tissue was partly invading mouse’s pancreas islet. The border and the construction of islet was still clear. (b) Tumor tissue had totally invaded pancreas islet. The border and the construction of islet was hazy. (c) Tumor cells had totally occupied pancreas islet. The whole islet was full of tumor cells. (d) Antigen FAP was positive in the fibroblasts of tumor stroma, but negative in the heart, liver, kidney and lungs.
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