Research Article
[Retracted] Diagnostic and Prognostic Value of DACH1 Methylation in the Sensitivity of Esophageal Cancer to Radiotherapy
Table 4
Relationship between methylation status of DACH1 and clinicopathological characteristics of patients with esophageal cancer (n, %).
| | Clinicopathological features | Number of cases | DACH1 | χ2 value | P value | | Methylation | Unmethylation |
| | Gender | | Male | 39 | 13 (33.33) | 26 (66.67) | 0.148 | 0.700 | | Female | 31 | 9 (29.03) | 22 (70.97) |
| | Age (years) | | <60 | 26 | 7 (26.92) | 19 (73.08) | 0.390 | 0.533 | | ≥60 | 44 | 15 (34.09) | 29 (65.91) |
| | Lesion site | | Upper thoracic segment | 28 | 10 (35.71) | 18 (64.29) | 0.735 | 0.693 | | Mid-thorax | 25 | 8 (32.00) | 17 (68.00) | | Lower thoracic segment | 17 | 4 (23.53) | 13 (76.47) |
| | Tumor length (cm) | | ≤5 | 41 | 15 (36.59) | 26 (63.41) | 1.221 | 0.269 | | >5 | 29 | 7 (24.14) | 22 (75.86) |
| | TNM staging | | Phase I-II | 45 | 7 (15.56) | 38 (84.44) | 14.731 | <0.001 | | Phase III-IV | 25 | 15 (60.00) | 10 (40.00) |
| | Degree of tumor differentiation | | High differentiation | 35 | 5 (14.29) | 30 (85.71) | 11.136 | 0.004 | | Middle divergence | 20 | 8 (40.00) | 12 (60.00) | | Low differentiation | 15 | 9 (60.00) | 6 (40.00) |
| | Lymph node metastasis | | Yes | 24 | 12 (50.00) | 12 (50.00) | 5.845 | 0.016 | | No | 46 | 10 (21.74) | 36 (78.26) |
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