Evaluation of Four eGFR Calculating Formulae in Predicting Postoperative Acute Kidney Injury in Adult Patients Undergoing Open-Heart Surgery with Cardiopulmonary Bypass

Table 5

ROC analysis of eGFR diagnosis of AKI.

Index	Cutoff	AUC (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)
Before surgery
Creatinine	91.00	0.623 (0.558–0.688)	0.346 (0.266, 0.426)	0.857 (0.802, 0.912)
CG	85.23	0.658 (0.595–0.721)	0.728 (0.653, 0.803)	0.552 (0.473, 0.631)
Correct CG	66.42	0.699 (0.639–0.760)	0.691 (0.614, 0.769)	0.643 (0.567, 0.719)
Simplify MDRD	88.66	0.648 (0.584–0.712)	0.588 (0.506, 0.671)	0.682 (0.608, 0.755)
CKD-EPI	92.39	0.673 (0.611–0.735)	0.662 (0.582, 0.741)	0.643 (0.567, 0.719)
Surgery day
Creatinine	67.70	0.721 (0.663–0.780)	0.831 (0.768, 0.894)	0.533 (0.454, 0.611)
CG	78.47	0.737 (0.679–0.794)	0.684 (0.606, 0.762)	0.682 (0.608, 0.755)
Correct CG	66.59	0.774 (0.720–0.828)	0.779 (0.710, 0.849)	0.675 (0.601, 0.749)
Simplify MDRD	90.71	0.743 (0.687–0.799)	0.750 (0.677, 0.823)	0.623 (0.547, 0.700)
CKD-EPI	97.73	0.761 (0.706–0.815)	0.831 (0.768, 0.894)	0.571 (0.493, 0.650)
1 day
Creatinine	90.90	0.854 (0.809–0.899)	0.802 (0.734, 0.869)	0.773 (0.707, 0.839)
CG	59.34	0.840 (0.793–0.887)	0.728 (0.653, 0.803)	0.838 (0.779, 0.896)
Correct CG	54.37	0.871 (0.829–0.914)	0.838 (0.776, 0.900)	0.779 (0.714, 0.845)
Simplify MDRD	67.30	0.869 (0.827–0.912)	0.7647 (0.693, 0.836)	0.857 (0.802, 0.912)
CKD-EPI	70.83	0.874 (0.832–0.916)	0.824 (0.759, 0.888)	0.805 (0.743, 0.867)
2 days
Creatinine	99.10	0.872 (0.830–0.914)	0.735 (0.661, 0.809)	0.903 (0.856, 0.949)
CG	61.74	0.846 (0.799–0.893)	0.802 (0.734, 0.869)	0.786 (0.721, 0.851)
Correct CG	50.40	0.875 (0.832–0.918)	0.802 (0.734, 0.869)	0.812 (0.750, 0.873)
Simplify MDRD	68.73	0.891 (0.851–0.931)	0.838 (0.776, 0.900)	0.805 (0.743, 0.868)
CKD-EPI	65.99	0.887 (0.847–0.928)	0.809 (0.743, 0.875)	0.831 (0.772, 0.890)