Research Article

Clinical Features of Dermatomyositis/Polymyositis with Anti-MDA5 Antibody Positivity

Table 4

Comparison of treatment regimens between the positive and negative groups (n (%)).

Positive anti-MDA5 antibody (n = 18)Negative anti-MDA5 antibody (n = 46)χ 2P

Treatment 18 (44.4)15 (32.6)0.2220.637
Treatment 210 (55.6)22 (47.8)4.5000.034
Treatment 309 (19.6)9.0000.002

Note. Chi-square test; Treatment 1: methylprednisolone ≥ 60 mg/d + immunosuppression; Treatment 2: methylprednisolone < 60 mg/d (or oral equivalent prednisone) + immunosuppression; Treatment 3: hormones only without combined immunosuppression.