Research Article

Preoperative Body Composition Combined with Tumor Metabolism Analysis by PET/CT Is Associated with Disease-Free Survival in Patients with NSCLC

Table 2

Relationship between primary tumor SUVmax, body composition, and clinical features.

Characteristic (mean ± SD)SUVmax
Low (n = 77)High (n = 77)P

Gender (%)0.379
 Female26 (33.8)20 (26.0)
 Male51 (66.2)57 (74.0)
Age60.00 [53.00, 66.00]59.00 [51.00, 64.00]0.253
BMI21.78 [19.78, 24.17]23.19 [21.10, 25.34]0.015
SMA (cm2)106.35 (21.00)115.08 (22.01)0.013
SMI43.61 (3.94)44.03 (4.36)0.533
SMD (HU)43.68 (3.08)44.33 (3.38)0.212
VFA (cm2)92.86 [61.96, 137.17]123.08 [72.69, 166.21]0.005
VATI34.48 [23.28, 53.16]45.40 [28.42, 61.33]0.017
SVR1.10 [0.78, 1.60]0.90 [0.70, 1.38]0.065
Sarcopenia (%)0.872
 Without38 (49.4)36 (46.8)
 With39 (50.6)41 (53.2)
Pathology (%)0.002
 Adenocarcinoma54 (70.1)34 (44.2)
 Squamous carcinoma23 (29.9)43 (55.8)
Differentiation (%)<0.001
 Poor19 (24.7)31 (40.3)
 Moderate33 (42.9)40 (51.9)
 Well25 (32.5)6 (7.8)
SUVmax
Liver SUVmean2.09 [1.87, 2.46]2.25 [2.01, 2.49]0.09
Spleen SUVmean1.84 [1.60, 2.03]1.91 [1.72, 2.03]0.208
AJCC stage<0.001
 Stage I51 (66.2)22 (28.6)
 Stage II16 (20.8)30 (39.0)
 Stage III10 (13.0)25 (32.5)
T stage (%)<0.001
 T153 (68.8)15 (19.5)
 T219 (24.7)42 (54.5)
 T34 (5.2)12 (15.6)
 T41 (1.3)8 (10.4)
N stage (%)0.052
 N059 (76.6)45 (58.4)
 N19 (11.7)15 (19.5)
 N29 (11.7)17 (22.1)

Non-normal distribution, quartile.