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| Quantitative parameters of CEUS | Description |
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| Basic measurement | |
| Peak intensity (PI) (dB) | A parameter corresponding to the maximum achieved intensity |
| Time to peak (TTP)(sec) | Time from the moment of the contrast medium administration until the maximum intensity value is reached |
| Time from peak to one half (TFPTOH)(sec) | Time from the peak-intensity value to the half value of peak intensity during the wash-out period |
| Wash-in slope (WIS)(dB/sec) | A parameter represents how fast the contrast agent fills the selected region, indicating vascularization |
| Derived indices | |
| PI index | The ratio between the PI values from the ROI of the nodule and the ROI of surrounding thyroid tissue |
| TTP index | The ratio between the TTP values from the ROI of the nodule and the ROI of surrounding thyroid tissue |
| TFPTOH index | The ratio between the TFPTOH values from the ROI of the nodule and the ROI of surrounding thyroid tissue |
| WIS index | The ratio between the WIS values from the ROI of the nodule and the ROI of surrounding thyroid tissue |
| Additional parameters | |
| Echo mean—lesion peak | Echo mean in lesion at the time of peak |
| Echo mean—surrounding parenchyma | Echo mean in surrounding tissue at the time of peak |
| Echo standard deviation—lesion peak | Echo standard deviation in lesion at the time of peak |
| Echo standard deviation—surrounding parenchyma | Echo standard deviation in surrounding tissue at the time of peak |
| Heterogeneity parameters | |
| HVp | Heterogeneity value at the time of peak |
| HRp | Heterogeneity ratio at the time of peak |
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