Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitative and Quantitative CEUS Characteristics

Table 6

The ROC analysis of quantitative characteristics.

ROC analysis of quantitative characteristics	AUC (%)	value	Cut-off	Sensitivity (%)	Specificity (%)	Overall accuracy (%)
PI	50.8	0.467	6.5	58.3	64.8	63.6
TFPTOH	60.6	0.876	34.5	83.8	55.6	60.6
WIS	54.5	0.688	1.4	66.7	50.0	53.0
TTP	57.1	0.780	13.8	100	22.2	36.4
PI index	50.1	0.506	1.32	30.8	81.8	72.1
TFPTOH index	63.9	0.941	1.21	38.5	89.1	79.4
WIS index	51.6	0.432	0.56	30.8	89.1	77.9
TTP index	50.1	0.500	1.03	84.6	30.9	41.2
HVp	59.7	0.854	147.2	41.7	79.6	72.7
HRp	50.8	0.467	0.88	33.3	81.5	72.7

TFPTOH, WIS, TTP values, PI index, TFPTOH index, and HVp values greater than or equal to the cut-off were considered malignant. In contrast, for PI values, WIS index, TTP index, and HRp parameter, values less than or equal to the cut-off were considered malignant.