Research Article

PD-L1 rs2890658 Polymorphism Increases Risk for Non-Small-Cell Lung Cancer in Northern China Population Based on Experimental Data and Meta-Analysis

Table 2

Genotype and allele frequencies of PD-L1 rs2890658 polymorphism in NSCLC and control population.

SNPsGenotypesCase (n = 600)Controls (n = 600)OR (95%CI)

PD-L1 rs2890658

Codominant modelAA177 (29.5)197 (32.8)1.00ref
AC255 (42.5)316 (52.7)0.90 (0.69–1.17)0.421
CC168 (28.0)87 (14.5)2.15 (1.55–2.99)<0.001

AlleleA609 (50.8)710 (59.2)1.00ref
C591 (49.2)490 (40.8)1.41 (1.20–1.65)<0.001

PD-L1, programmed cell death ligand-1; NSCLC, non-small-cell lung cancer.