The Value of Brain Structural Magnetic Resonance Imaging Combined with APOE--ε4 Genotype in Early Diagnosis and Disease Progression of Senile Vascular Cognitive Impairment No Dementia
Table 2
Baseline data of patients.
Features
NC group (n = 50)
VCIND group (n = 130)
X2/t/z
P
Gender (%)
0.771
0.380
Male
26 (52.0)
77 (59.2)
Female
24 (48.0)
53 (40.8)
Age (years)
67.36 ± 10.95
68.65 ± 11.1
0.703
0.483
BMI (kg/m2）
24.20 ± 3.98
24.52 ± 4.00
0.486
0.627
Years of education
6.14 (5–7)
5.52 (5–6)
2.604
0.009
Stroke onset time (h)
8 (7–9)
8 (7–9)
0.895
0.371
Hypertension (%)
6.304
0.012
Without
25 (50.0)
39 (30.0)
With
25 (50.0)
91 (70.0)
Diabetes (%)
2.465
0.116
Without
37 (74.0)
80 (61.5)
With
13 (26.0)
50 (38.5)
Coronary heart disease (%)
0.051
0.821
Without
40 (80.0)
102 (78.5)
With
10 (20.0)
28 (21.5)
Smoking history (%)
0.548
0.459
Without
41 (82.0)
100 (76.9)
With
9 (18.0)
30 (23.1)
Drinking history (%)
0.565
0.452
Without
36 (72.0)
86 (66.2)
With
14 (28.0)
44 (33.8)
Fasting blood glucose
5.53 ± 0.99
5.58 ± 0.97
0.312
0.755
Triglycerides (TG）
2.27 ± 0.86
2.35 ± 0.77
0.575
0.566
Cholesterol (TC）
4.85 ± 1.07
5.10 ± 0.81
1.682
0.094
High-density lipoprotein (HDL)
1.20 ± 0.26
1.15 ± 0.28
1.044
0.298
Low-density lipoprotein (LDL）
2.76 ± 1.09
2.89 ± 0.95
0.792
0.429
Homocysteine (hcy) (%）
14.014
≤0.001
＜13.9 mol/L
40 (80.0)
64 (49.2)
≥13.9 mol/L
10 (20.0)
66 (50.8)
Values are mean ± SD or n (%) or median (P25, P75). NC, normal control; VCIND, vascular cognitive impairment no dementia.
