Assessment of Antioxidant Enzyme Superoxide Dismutase (SOD) in Oral Cancer: Systematic Review and Meta-Analysis

Table 4

The SOD enzyme activity level changes in different samples of patients with various histopathological grades of OSCC.

Author	Sample		OSCC (WD)	OSCC (MD)	OSCC (PD)	Measure	Stat Sig	H/P grade
	Type	Size	Mean ± SD	Mean ± SD	Mean ± SD	Unit	P-value	Criteria
Patel et al. [26]	Er	126	2212.4 ± 112.3	2,137 ± 76.2	2199.5 ± 244.2	U/mg Hb	0.046	—
Singh et al. [39]	Sa	50	0.026 ± 0.035	0.027 ± 0.021	0.029 ± 0.027	U/mg	0.961	Woolgar and Scott [66]
Rai et al. [41]	Pl	20	59.22 ± 4.01	58.43 ± 2.26	—	—	<0.001	Akhter et al. [67]

OSCC-oral squamous cell carcinoma, WD-well-differentiated, MD-moderately differentiated, PD-poorly differentiated, Stat Sig-statistical significance, SD-standard deviation, Sa-saliva, Pl-plasma, and Er-erythrocyte.