Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Virulence factors</td><td class="align_center">Potential virulence classes</td><td class="align_center">Related virulence genes and operons</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Acinetobactin</td><td class="align_center">Iron uptake</td><td class="align_center">barAB, basABCDFGHIJ, bauABCDEF, and entE</td></tr><tr><td class="align_left">Heme utilization</td><td class="align_center">Iron uptake</td><td class="align_center">hemO</td></tr><tr><td class="align_left">AdeFGH efflux pump</td><td class="align_center">Biofilm formation</td><td class="align_center">adeFGH</td></tr><tr><td class="align_left">Biofilm-associated protein</td><td class="align_center">Biofilm formation</td><td class="align_center">Bap</td></tr><tr><td class="align_left">Csu pili</td><td class="align_center">Biofilm formation</td><td class="align_center">csuABCDE</td></tr><tr><td class="align_left">PNAG</td><td class="align_center">Biofilm formation</td><td class="align_center">pgaABCD</td></tr><tr><td class="align_left">LPS</td><td class="align_center">Immune invasion</td><td class="align_center">lpsB and lpxABCDLM</td></tr><tr><td class="align_left">Phospholipase C and D</td><td class="align_center">Enzyme production</td><td class="align_center">plc1, plc2, and plcD</td></tr><tr><td class="align_left">Outer membrane protein</td><td class="align_center">Adherence</td><td class="align_center">ompA</td></tr><tr><td class="align_left">Quorum sensing</td><td class="align_center">Regulation</td><td class="align_center">abaIR</td></tr><tr><td class="align_left">Two-component system</td><td class="align_center">Regulation</td><td class="align_center">bfmRS</td></tr><tr><td class="align_left">pbpG</td><td class="align_center">Serum resistance</td><td class="align_center">pbpG</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>PNAG, polysaccharide poly-N-acetylglucosamine. </div></td></tr></table>

<div>Computational identification of genes encoding for virulence factors of AB073.</div>

Global Health, Epidemiology and Genomics

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Table 2

Table 2: Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand

Table 2 | Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand 