Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia

Table 2

Proportion of T/T homozygotes for rs2114724 among male and female patients.

Genotype	Males	Females	Chi-square analysis
T/T	52 (41) [2.95]	22 (33) [3.67]	Total χ^2 = 12.22; degrees of freedom = 2; value = 0.002
C/T	71 (70) [0.01]	54 (55) [0.02]
C/C	47 (59) [2.44]	58 (46) [3.13]

Individual χ² values obtained using a 2 × 3 contingency are shown in square brackets. The expected number of males and females is given in parentheses.