Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations
Table 3
Comparison of the genotypes and serum lipid levels in the Maonan and Han populations.
Group/genotype
n
TC (mmol/L)
TG (mmol/L)
HDL-C (mmol/L)
LDL-C (mmol/L)
ApoA1 (g/L)
ApoB (g/L)
ApoA1/ApoB
Maonan
633
CC
184
5.00 ± 0.96
1.22 (0.90)
1.61 ± 0.39
2.91 ± 0.83
1.39 ± 0.23
0.89 ± 0.19
1.64 ± 0.55
CT
336
5.02 ± 0.97
1.29 (0.87)
1.65 ± 0.40
2.90 ± 0.79
1.41 ± 0.24
0.88 ± 0.19
1.68 ± 0.49
TT
113
4.89 ± 0.96
1.35 (0.86)
1.53 ± 0.34
2.79 ± 0.81
1.34 ± 0.22
0.86 ± 0.19
1.62 ± 0.42
F
0.779
2.052
3.281
1.366
2.756
1.173
0.329
0.459
0.358
0.038
0.256
0.064
0.310
0.720
CC/CT
520
5.01 ± 0.97
1.26 (0.88)
1.64 ± 0.40
2.91 ± 0.81
1.40 ± 0.24
0.89 ± 0.19
1.67 ± 0.51
F
1.509
−1.389
4.844
2.712
3.721
2.109
0.024
0.220
0.165
0.028
0.100
0.054
0.147
0.876
Han
646
CC
230
4.83 ± 0.88
1.11 (0.47)
1.88 ± 0.44
2.78 ± 0.59
1.39 ± 0.22
0.87 ± 0.20
1.67 ± 0.44
CT
321
4.94 ± 0.92
1.12 (0.74)
1.79 ± 0.41
2.85 ± 0.73
1.36 ± 0.23
0.87 ± 0.19
1.65 ± 0.46
TT
95
4.98 ± 1.04
0.98 (0.87)
1.85 ± 0.41
2.97 ± 0.83
1.38 ± 0.23
0.88 ± 0.21
1.65 ± 0.50
F
1.409
3.369
2.719
2.710
1.059
0.394
0.070
P
0.245
0.186
0.067
0.067
0.347
0.674
0.933
CC/CT
551
4.89 ± 0.91
1.11 (0.62)
1.82 ± 0.42
2.82 ± 0.68
1.38 ± 0.23
0.87 ± 0.20
1.66 ± 0.45
F
0.774
−1.578
1.132
3.615
0.457
0.493
0.034
0.379
0.144
0.288
0.058
0.499
0.483
0.853
TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; ApoA1/ApoB: the ratio of apolipoprotein A1 to apolipoprotein B. The value of TG was presented as median (interquartile range); the difference between the genotypes was determined by the Wilcoxon–Mann–Whitney test.