Research Article
Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations
Table 5
Relationship between serum lipid parameters and relative factors in the Maonan and Han populations.
| Lipid | Risk factor | B | Std. error | Beta | t | |
| Maonan and Han | | | | | | |
| TC | Waist circumference | 0.018 | 0.003 | 0.162 | 5.487 | <0.001 | Age | 0.007 | 0.002 | 0.106 | 3.688 | <0.001 | Height | −0.010 | 0.003 | −0.088 | −2.987 | 0.003 | Diastolic blood pressure | 0.005 | 0.002 | 0.066 | 2.293 | 0.022 |
| TG | Waist circumference | 0.038 | 0.003 | 0.302 | 11.155 | <0.001 | Alcohol consumption | 0.298 | 0.073 | 0.109 | 4.106 | <0.001 | Glucose | 0.069 | 0.022 | 0.082 | 3.142 | 0.002 | Diastolic blood pressure | 0.008 | 0.003 | 0.081 | 3.024 | 0.003 |
| HDL-C | Waist circumference | −0.012 | 0.002 | −0.245 | −6.804 | <0.001 | Ethnic group | 0.189 | 0.022 | 0.225 | 8.779 | <0.001 | Alcohol consumption | 0.135 | 0.033 | 0.128 | 4.045. | <0.001 | Gender | 0.123 | 0.031 | 0.143 | 3.996 | <0.001 | Age | 0.003 | 0.001 | 0.090 | 3.163 | 0.002 | Body mass index | −0.010 | 0.004 | −0.082 | −2.338 | 0.020 | Pulse pressure | −0.002 | 0.001 | −0.060 | −2.123 | 0.034 | Cigarette smoking | 0.067 | 0.033 | 0.067 | 1.987 | 0,047 |
| LDL-C | Waist circumference | 0.017 | 0.003 | 0.199 | 6.917 | <0.001 | Age | 0.007 | 0.001 | 0.125 | 4.499 | <0.001 | Height | −0.009 | 0.003 | −0.096 | −3.291 | 0.001 |
| ApoA1 | Waist circumference | −0.003 | 0.001 | −0.103 | −2.453 | 0.014 | Alcohol consumption | 0.152 | 0.019 | 0.264 | 7.792 | <0.001 | Gender | 0.076 | 0.018 | 0.162 | 4.191 | <0.001 | Cigarette smoking | 0.064 | 0.019 | 0.117 | 3.311 | 0.001 | Weight | −0.003 | 0.001 | −0.127 | −2.831 | 0.005 |
| ApoB | Waist circumference | 0.006 | 0.001 | 0.280 | 10.346 | <0.001 | Age | 0.002 | 0.000 | 0.136 | 4.914 | <0.001 | Diastolic blood pressure | 0.001 | 0.000 | 0.073 | 2.624 | 0.009 | Glucose | 0.010 | 0.004 | 0.065 | 2.399 | 0.017 |
| ApoA1/ApoB | Waist circumference | −0.014 | 0.002 | −0.244 | −6.668 | <0.001 | Alcohol consumption | 0.214 | 0.038 | 0.180 | 5.552 | <0.001 | Gender | 0.161 | 0.035 | 0.166 | 4.532 | <0.001 | Age | −0.003 | 0.001 | −0.082 | −3.065 | 0.002 | Body mass index | −0.015 | 0.005 | −0.107 | −2.998 | 0.003 | Cigarette smoking | 0.089 | 0.039 | 0.079 | 2.294 | 0.022 | Glucose | −0.022 | 0.010 | −0.060 | −2.234 | 0.026 |
| Maonan | | | | | | | TC | Waist circumference | 0.025 | 0.004 | 0.233 | 5.810 | <0.001 | Age | 0.011 | 0.003 | 0.165 | 4.291 | <0.001 | Gender | 0.285 | 0.079 | 0.144 | 3.601 | <0.001 |
| TG | Waist circumference | 0.038 | 0.004 | 0.345 | 9.209 | <0.001 | Glucose | 0.084 | 0.029 | 0.106 | 2.904 | 0.004 | Diastolic blood pressure | 0.007 | 0.003 | 0.089 | 2.367 | 0.018 | Alcohol consumption | 0.201 | 0.090 | 0.083 | 2.227 | 0.026 |
| HDL-C | Waist circumference | −0.014 | 0.002 | −0.333 | −8.635 | <0.001 | Genotype | −0.112 | 0.038 | −0.110 | −2.971 | 0.003 | Alcohol consumption | 0.150 | 0.044 | 0.157 | 3.444 | 0.001 | Gender | 0.094 | 0.038 | 0.117 | 2.503 | 0.013 |
| LDL-C | Waist circumference | 0.023 | 0.004 | 0.262 | 6.566 | <0.001 | Gender | 0263 | 0.066 | 0.160 | 4.018 | <0.001 | Age | 0.009 | 0.002 | 0.152 | 3.981 | <0.001 |
| ApoA1 | Waist circumference | −0.006 | 0.001 | −0.219 | −5.605 | <0.001 | Alcohol consumption | 0.140 | 0.027 | 0.245 | 5.132 | <0.001 | Gender | 0.101 | 0.026 | 0.211 | 3.909 | <0.001 | Cigarette smoking | 0.082 | 0.029 | 0.143 | 2.829 | 0.005 | Genotype | −0.054 | 0.023 | −0.089 | −2.361 | 0.019 |
| ApoB | Waist circumference | 0.008 | 0.001 | 0.385 | 10.056 | <0.001 | Age | 0.002 | 0.000 | 0.181 | 4.945 | <0.001 | Gender | 0.042 | 0.015 | 0.109 | 2.866 | 0.040 |
| ApoA1/ApoB | Waist circumference | −0.022 | 0.002 | −0.390 | −10.608 | <0.001 | Alcohol consumption | 0.224 | 0.045 | 0.184 | 4.499 | <0.001 | Age | −0.004 | 0.001 | −0.110 | −3.023 | 0.003 |
| Han | | | | | | | TC | Diastolic blood pressure | 0.011 | 0.003 | 0.128 | 3.153 | 0.002 | Age | 0.006 | 0.003 | 0.098 | 2.478 | 0.013 | Body mass index | 0.024 | 0.012 | 0.085 | 2.126 | 0.034 |
| TG | Waist circumference | 0.039 | 0.006 | 0.266 | 6.837 | <0.001 | Alcohol consumption | 0.370 | 0.114 | 0.123 | 3.249 | 0.001 | Diastolic blood pressure | 0.008 | 0.004 | 0.077 | 1.995 | 0.046 |
| HDL-C | Waist circumference | −0.011 | 0.003 | −0.215 | −3.871 | <0.001 | Body mass index | −0.016 | 0.007 | −0.120 | −2.159 | 0.031 |
| LDL-C | Age | 0.007 | 0.002 | 0.155 | 4.003 | <0.001 | Body mass index | 0.031 | 0.008 | 0.140 | 3.608 | <0.001 |
| ApoA1 | Alcohol consumption | 0.168 | 0.023 | 0.288 | 7.189 | <0.001 | Weight | −0.007 | 0.001 | −0.282 | −7.052 | <0.001 |
| ApoB | Waist circumference | 0.005 | 0.001 | 0.189 | 4.863 | <0.001 | Gender | −0.100 | 0.018 | −0.248 | −5.554 | <0.001 | Diastolic blood pressure | 0.003 | 0.001 | 0.142 | 3.766 | <0.001 | Glucose | 0.018 | 0.005 | 0.121 | 3.286 | 0.001 | Height | −0.003 | 0.001 | −0.121 | −2.675 | 0.008 |
| ApoA1/ApoB | Body mass index | −0.039 | 0.005 | −0.275 | −7.287 | <0.001 | Glucose | −0.042 | 0.013 | −0.124 | −3.360 | <0.001 | Gender | 0.213 | 0.040 | 0.232 | 5.359 | 0.001 | Alcohol consumption | 0.231 | 0.051 | 0.200 | 4.540 | <0.001 | Diastolic blood pressure | −0.004 | 0.002 | −0.105 | −2.824 | 0.005 |
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TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; ApoA1/ApoB: the ratio of apolipoprotein A1 to apolipoprotein B; B: unstandardized coefficient; Beta: standardized coefficient.
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