Association between the PLTP rs4810479 SNP and Serum Lipid Traits in the Chinese Maonan and Han Populations
Table 6
Relationship between serum lipid parameters and relative factors in the males and females of the Han and Maonan populations.
Lipid
Risk factor
B
Std. error
Beta
t
Maonan/male
TC
Weight
0.029
0.005
0.332
5.320
<0.001
Glucose
0.103
0.041
0.151
2.527
0.012
Pulse pressure
−0.010
0.003
−0.190
−2.831
0.005
Age
0.010
0.004
0.161
2.276
0.024
TG
Waist circumference
0.054
0.008
0.401
6.975
<0.001
Glucose
0.179
0.054
0.191
3.321
0.001
Alcohol consumption
0.365
0.142
0.148
2.574
0.011
HDL-C
Waist circumference
−0.015
0.002
−0.353
−6.195
<0.001
Alcohol consumption
0.170
0.044
0.221
3.883
<0.001
Genotype
−0.134
0.057
−0.133
−2.348
0.020
LDL-C
Weight
0.024
0.005
0.310
4.954
<0.001
Alcohol consumption
−0.203
0.095
−0.128
−2.123
0.035
Pulse pressure
−0.010
0.003
−0.212
−3.143
0.002
Age
0.009
0.004
0.164
2.297
0.022
ApoA1
Alcohol consumption
0.153
0.031
0.293
4.898
<0.001
Waist circumference
−0.005
0.002
−0.186
−3.231
0.001
Cigarette smoking
0.085
0.031
0.162
2.713
0.007
ApoB
Waist circumference
0.005
0.002
0.234
2.342
0.020
Glucose
0.025
0.008
0.183
3.254
0.001
Pulse pressure
−0.002
0.001
−0.200
−3.164
0.002
Age
0.002
0.001
0.179
2.638
0.009
Weight
0.004
0.002
0,242
2.319
0.021
ApoA1/ApoB
Waist circumference
−0.021
0.004
−0.343
−6.021
<0.001
Alcohol consumption
0.301
0.064
0.267
4.691
<0.001
Systolic blood pressure
0.003
0.001
0.131
2.313
0.022
Maonan/female
TC
Age
0.019
0.004
0.271
5.469
<0.001
Waist circumference
0.024
0.006
0.197
3.997
<0.001
Glucose
−0.085
0.042
−0.102
−2.035
0.043
TG
Waist circumference
0.033
0.004
0.357
7.518
<0.001
Age
0.008
0.003
0.143
3.009
0.003
HDL-C
Waist circumference
−0.014
0.002
−0.288
−5.861
<0.001
Genotype
−0.100
0.050
−0.098
−1.992
0.047
LDL-C
Age
0.013
0.003
0.235
4.870
<0.001
Waist circumference
0.020
0.005
0.209
4.264
<0.001
Alcohol consumption
0.619
0.297
0.102
2.086
0.038
AopA1
Waist circumference
−0.006
0.001
−0.221
−4.423
<0.001
Genotype
−0.067
0.028
−0.120
−2.406
0.017
ApoB
Waist circumference
0.008
0.001
0.351
7.481
<0.001
Age
0.004
0.001
0.276
5.847
<0.001
Glucose
−0.016
0.008
−0.097
−2.027
0.043
ApoA1/ApoB
Waist circumference
−0.020
0.003
−0.377
−7.697
<0.001
Systolic blood pressure
−0.003
0.001
−0.168
−3.545
<0.001
Height
0.010
0.004
0.139
2.907
0.004
Han/male
TC
Diastolic blood pressure
0.014
0.005
0.187
3.121
0.005
Genotype
0.360
0.159
0.136
2.269
0.024
TG
Waist circumference
0.051
0.010
0.290
4.939
<0.001
Alcohol consumption
0.380
0.165
0.135
2.302
0.022
HDL-C
Weight
−0.016
0.003
−0.299
−4.959
<0.001
Alcohol consumption
0.133
0.053
0.151
2.504
0.013
LDL-C
Genotype
0.372
0.119
0.186
3.136
0.002
Body mass index
0.029
0.012
0.149
2.507
0.013
Glucose
0.060
0.027
0.132
2.230
0.027
ApoA1
Alcohol consumption
0.193
0.030
0.368
6.383
<0.001
Weight
−0.008
0.002
−0.276
−4.784
<0.001
ApoB
Body mass index
0.012
0.004
0.197
3.322
0.001
Glucose
0.028
0.008
0.199
3.426
0.001
Diastolic blood pressure
0.003
0.001
0.159
2.681
0.008
ApoA1/ApoB
Weight
−0.019
0.003
−0.337
−5.821
<0.001
Alcohol consumption
0.234
0.058
0.239
4.050
<0.001
Glucose
−0.051
0.019
−0.156
−2.717
0.007
Han/female
TC
Age
0.014
0.004
0.208
3.986
<0.001
Height
−0.020
0.008
−0.130
−2.505
0.013
TG
Waist circumference
0.029
0.006
0.234
4.573
<0.001
Diastolic blood pressure
0.014
0.005
0.145
2.825
0.005
HDL-C
Waist circumference
−0.009
0.004
−0.184
−2.259
0.024
Body mass index
−0.023
0.011
−0.169
−2.077
0.039
LDL-C
Age
0.014
0.003
0.265
5.363
<0.001
Body mass index
0.027
0.012
0.112
2.275
0.023
ApoA1
Body mass index
−0.015
0.003
−0.220
−4.364
<0.001
ApoB
Age
0.004
0.001
0.286
5.829
<0.001
Body mass index
0.012
0.003
0.205
4.241
<0.001
Cigarette smoking
−0.156
0.058
−0.130
−2.663
0.008
ApoA1/ApoB
Age
−0.006
0.001
−0.209
−4.279
<0.001
Cigarette smoking
0.413
0.133
−0.151
3.096
0.002
Body mass index
−0.040
0.007
−0.287
−5.970
<0.001
TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; ApoA1/ApoB: the ratio of apolipoprotein A1 to apolipoprotein B; B: unstandardized coefficient; Beta: standardized coefficient. The correlation among serum lipid parameters and the genotypes and several environmental factors was determined by multivariable linear regression analyses with stepwise modeling.