Reduced Concentrations of NSE, S100β, Aβ, and Proinflammatory Cytokines in Elderly Patients Receiving Ultrasound-Guided Combined Lumbar Plexus-Sciatic Nerve Block during Hip Replacement

Table 4

Expression of biomarkers of cognitive function in the two groups.

Treatments	N	NSE		S100β		Aβ
		Before surgery	10 days after surgery	Before surgery	10 days after surgery	Before surgery	10 days after surgery
Ultrasound-guided combined lumbar plexus-sciatic nerve block	58	8.78 ± 1.55	10.23 ± 0.26	237.24 ± 33.31	267.37 ± 41.28	259.15 ± 30.50	286.81 ± 21.75
Combined spinal-epidural anesthesia	62	9.09 ± 1.93	10.60 ± 0.22^a	242.63 ± 26.83	283.93 ± 26.05^a	256.27 ± 30.25	298.28 ± 37.60^a
T		0.966	8.434	0.979	2.646	0.519	2.027
P		0.336	<0.0001	0.330	0.009	0.605	0.045

indicates compared with combined spinal-epidural anesthesia; ^a indicates compared with that before surgery.