Research Article

Reduced Concentrations of NSE, S100β, Aβ, and Proinflammatory Cytokines in Elderly Patients Receiving Ultrasound-Guided Combined Lumbar Plexus-Sciatic Nerve Block during Hip Replacement

Table 5

Proinflammatory cytokine levels in the two groups.

TreatmentsNIL-6TNF-αIL-1βHs-CRP
Before surgery10 days after surgeryBefore surgery10 days after surgeryBefore surgery10 days after surgeryBefore surgery10 days after surgery

Ultrasound-guided combined lumbar plexus-sciatic nerve block5852.11 ± 12.01102.30 ± 36.9848.35 ± 13.4780.88 ± 22.7835.72 ± 3.8245.54 ± 5.6818.42 ± 0.1923.93 ± 2.60

Combined spinal-epidural anesthesia6253.86 ± 11.85124.53 ± 41.31a44.17 ± 11.11101.56 ± 27.04a35.66 ± 4.8350.90 ± 5.59a18.5 ± 0.2928.02 ± 2.17a

T0.8033.0981.8594.5150.0755.2081.7749.378

P0.42350.00240.0655<0.00010.940<0.00010.079<0.0001

indicates compared with combined spinal-epidural anesthesia; aindicates compared with that before surgery.