Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China

Table 5

Univariate and multivariate logistics regression analyses for CR in all participants.

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)	value	OR (95% CI)	value
Age	1.08 (1.04, 1.12)	<0.001	1.08 (1.02, 1.13)	0.005
Glycosylated hemoglobin	2.00 (1.19, 3.39)	0.010	Excluded
APTT	0.86 (0.78, 0.96)	0.006	0.81 (0.69, 0.95)	0.011
Sex			Excluded
Male	Reference
Female	3.10 (1.15, 8.32)	0.025
Aspirin resistance
No	Reference		Reference
Yes	6.91 (2.73, 17.48)	<0.001	6.47 (2.02, 20.67)	0.002
Diabetes			Excluded
No	Reference
Yes	3.47 (1.45, 8.32)	0.005
Coronary heart disease type, n (%)		0.073		0.053
STEMI	Reference		Reference
NSTEMI	0.41 (0.11, 1.59)	0.198	0.19 (0.03, 1.12)	0.066
SAP	5.37 (1.08, 26.81)	0.040	4.43 (0.57, 34.57)	0.156
UA	0.99 (0.35, 2.79)	0.987	0.39 (0.10, 1.55)	0.181