Differentially Expressed microRNAs in Peritoneal Dialysis Effluent-Derived Exosomes from the Patients with Ultrafiltration Failure

Figure 2

Screen of differentially expressed miRNAs (DE-miRNAs) between the exosomes from the failed ultrafiltration PDE and successful ultrafiltration PDE. (a) Based on the different values , , and ), DE-miRNAs were screened. (b) Volcano plots of the 70 DE-miRNAs with |log2 (fold change) |>1 and . The blue points represent the downregulation; the gray points represent the normal; and the red points represent the upregulation in the exosomes from the failed ultrafiltration PDE compared with the exosomes from the successful ultrafiltration PDE. (c) The bidirectional hierarchical clustering heatmap of the 19 DE-miRNAs with . UFF: the exosomes from the failed ultrafiltration PDE; control: the exosomes from the successful ultrafiltration PDE.

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