circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis

Figure 1

CRC is associated with circRNA_101277 upregulation. (a) Hierarchical clustering analyses were used to detect differences in circRNA expression profiles between CRC and healthy tissues. (b) Relative circRNA_101277 levels were measured in normal tissues and CRC tissues. (c) circRNA_101277 levels in 100 pairs of CRC and healthy tissues were assessed via qRT-PCR. (d) The overall survival of CRC patients with high circRNA_101277 expression was significantly worse than that of patients with low expression of this circRNA. (e) ROC curve analyses revealed that circRNA_101277 was able to effectively discriminate between tumor and adjacent tissues. p < 0.05.

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