Analysis of the APOB Gene and Apolipoprotein B Serum Levels in a Mexican Population with Acute Coronary Syndrome: Association with the Single Nucleotide Variants rs1469513, rs673548, rs676210, and rs1042034
Table 3
Genotype and allele distribution of the rs1469513, rs673548, rs676210, and rs1042034 in the APOB gene in CG and ACSG.
CG n (%)
ACSG n (%)
OR CI (95%)
rs1469513
Genotype
T/T
99 (33)
113 (37.7)
—
—
T/C
143 (47.7)
143 (47.7)
0.87 (0.61–1.25)
0.466
C/C
58 (19.3)
44 (14.6)
0.66 (0.41–1.07)
0.090
Allele
T
341 (58.8)
369 (61.5)
—
—
C
259 (43.2)
231 (38.5)
0.82 (0.65–1.03)
0.100
rs673548
Genotype
G/G
181 (60.3)
151 (50.3)
—
—
G/A
98 (32.7)
125 (41.7)
1.53 (1.08–2.15)
0.014
A/A
21 (7)
24 (8)
1.37 (0.734–2.55)
0.321
Allele
G
460 (76.66)
427 (71.16)
—
—
A
140 (23.33)
173 (28.8)
1.33 (1.02–1.72)
0.030
rs676210
Genotype
G/G
185 (61.7)
141 (47)
—
—
G/A
95 (31.7)
118 (39.3)
1.63 (1.15–2.31)
0.005
A/A
20 (6.6)
41 (13.7)
2.69 (1.50–4.79)
<0.001
Allele
G
465 (77.5)
400 (66.7)
—
—
A
135 (22.5)
200 (33.3)
1.72 (1.333–2.225)
<0.001
rs1042034
Genotype
C/C
160 (53.3)
165 (55)
—
—
T/C
111 (37)
120 (40)
1.05 (0.75–1.47)
0.784
T/T
29 (9.7)
15 (5)
0.50 (0.26–0.97)
0.037
Allele
C
431 (71.8)
450 (75)
—
—
T
169 (28.2)
150 (25)
0.85 (0.66–1.09)
0.214
CG (control group), ACSG (acute coronary syndrome group), OR (odds ratio), CI (confidence interval).
