Analysis of the APOB Gene and Apolipoprotein B Serum Levels in a Mexican Population with Acute Coronary Syndrome: Association with the Single Nucleotide Variants rs1469513, rs673548, rs676210, and rs1042034
Table 4
Differences between groups of the rs1469513, rs673548, rs676210, and rs1042034 by the inheritance model.
CG n (%)
ACSG n (%)
OR CI (95%)
rs1469513
Dominant model
T/T
99 (33)
113 (37.7)
—
—
T/C + C/C
201 (67)
187 (62.3)
0.81 (0.58–1.14)
0.231
Recessive model
T/T + T/C
242 (80.7)
256 (85.4)
C/C
58 (19.3)
44 (14.6)
0.71 (0.46–1.10)
0.128
rs673548
Dominant model
G/G
181 (60.3)
151 (50.3)
—
—
G/A + A/A
119 (39.7)
149 (49.7)
1.50 (1.08–2.07)
0.013
Recessive model
G/G + G/A
279 (93)
276 (92)
—
A/A
21 (7)
24 (8)
1.15 (0.62–2.12)
0.641
rs676210
Dominant model
G/G
185 (61.7)
141 (47)
—
—
G/A + A/A
115 (38.3)
159 (53)
1.81 (1.31–2.51)
<0.001
Recessive model
G/G + G/A
280 (93.4)
259 (86.3)
—
—
A/A
20 (6.6)
41 (13.7)
2.21 (1.265–3.88)
0.004
rs1042034
Dominant model
C/C
160 (53.3)
165 (55)
—
—
T/C + T/T
140 (46.7)
135 (45)
0.93 (0.67–1.28)
0.682
Recessive model
C/C + T/C
271 (90.3)
285 (95)
—
—
T/T
29 (9.7)
15 (5)
0.49 (0.25–0.93)
0.028
CG (control group), ACSG (acute coronary syndrome group), OR (odds ratio), CI (confidence interval).
