Research Article
TPX2 Serves as a Cancer Susceptibility Gene and Is Closely Associated with the Poor Prognosis of Endometrial Cancer
Table 2
Univariate/multivariate cox regression analysis for independent prognostic factors.
| Variables | Univariate analysis | Multivariate analysis | HR | 95% CI | value | HR | 95% CI | value |
| Age | <77/≥77 | 1.991 | 1.159–3.421 | 0.013 | 2.114 | 1.211–3.689 | 8.45E – 03 |
| Grade | G1-2/G3 | 3.715 | 2.162–6.381 | 2.00E – 06 | 1.310 | 0.699–2.455 | 0.400 |
| FIGO stage | I-II/III-IV | 4.174 | 2.743–6.351 | 2.50E – 11 | 2.706 | 1.726–4.240 | 1.41E – 05 |
| Histological types | Endometrioid/serous | 3.426 | 2.259–5.195 | 6.84E – 09 | 1.127 | 0.688–1.847 | 0.635 |
| TPX2 | low/high | 1.040 | 1.032–1.047 | 2.50E – 24 | 1.033 | 1.023–1.043 | 3.52E – 11 |
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HR: hazard ratio; CI: confidence interval; FIGO: fédération internationale de gynécologie et d’obstétrique.
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