Positive Expression of Retinol-Binding Protein 4 Is Related to the Malignant Clinical Features Leading to Poor Prognosis of Glioblastoma

Table 2

Univariate analyses of cancer-specific survival and overall survival of GBM patients.

Variables	Patients	Cancer-specific survival		Overall survival
	(n = 73)	Months	value	Months	values
Age (years)
≤63	38	23.6 ± 5.6		23.6 ± 5.6
>63	35	7.2 ± 2.6		5.8 ± 2.1
Sex
Female	31	11.8 ± 3.2	0.844	11.2 ± 3.1	0.747
Male	42	17.5 ± 4.8		16.2 ± 4.5
Location
Parietal lobe	13	16.5 ± 8.6	0.985	13.6 ± 7.4	0.971
Temporal lobe	25	11.4 ± 2.9		10.8 ± 2.8
Frontal lobe	32	17.4 ± 5.5		15.1 ± 4.7
Unknown	3	12.3 ± 6.2		12.3 ± 6.1
Tumor size
≤4.3 cm	38	19.5 ± 5.2	0.328	15.8 ± 4.3	0.846
>4.3 cm	35	13.8 ± 4.7		13.8 ± 4.7
Surgery
Local resection	39	19.8 ± 5.4	0.538	16.9 ± 4.7	0.262
Radical resection	16	6.6 ± 2.1		5.3 ± 1.8
Lobectomy	18	15.7 ± 6.6		14.6 ± 6.2
Chemotherapy
No	61	13.8 ± 3.7		13.1 ± 3.5	0.071
Yes	12	24.8 ± 5.9		22.3 ± 6.1
RBP4 expression
Negative	31	26.6 ± 6.8		22.6 ± 5.9
Positive	42	7.3 ± 1.7		6.9 ± 1.6

Note. Statistically significant.