Research Article
Positive Expression of Retinol-Binding Protein 4 Is Related to the Malignant Clinical Features Leading to Poor Prognosis of Glioblastoma
Table 2
Univariate analyses of cancer-specific survival and overall survival of GBM patients.
| Variables | Patients | Cancer-specific survival | Overall survival | (n = 73) | Months | value | Months | values |
| Age (years) | ≤63 | 38 | 23.6 ± 5.6 | | 23.6 ± 5.6 | | >63 | 35 | 7.2 ± 2.6 | | 5.8 ± 2.1 | | Sex | Female | 31 | 11.8 ± 3.2 | 0.844 | 11.2 ± 3.1 | 0.747 | Male | 42 | 17.5 ± 4.8 | | 16.2 ± 4.5 | | Location | Parietal lobe | 13 | 16.5 ± 8.6 | 0.985 | 13.6 ± 7.4 | 0.971 | Temporal lobe | 25 | 11.4 ± 2.9 | | 10.8 ± 2.8 | | Frontal lobe | 32 | 17.4 ± 5.5 | | 15.1 ± 4.7 | | Unknown | 3 | 12.3 ± 6.2 | | 12.3 ± 6.1 | | Tumor size | ≤4.3 cm | 38 | 19.5 ± 5.2 | 0.328 | 15.8 ± 4.3 | 0.846 | >4.3 cm | 35 | 13.8 ± 4.7 | | 13.8 ± 4.7 | | Surgery | Local resection | 39 | 19.8 ± 5.4 | 0.538 | 16.9 ± 4.7 | 0.262 | Radical resection | 16 | 6.6 ± 2.1 | | 5.3 ± 1.8 | | Lobectomy | 18 | 15.7 ± 6.6 | | 14.6 ± 6.2 | | Chemotherapy | No | 61 | 13.8 ± 3.7 | | 13.1 ± 3.5 | 0.071 | Yes | 12 | 24.8 ± 5.9 | | 22.3 ± 6.1 | | RBP4 expression | Negative | 31 | 26.6 ± 6.8 | | 22.6 ± 5.9 | | Positive | 42 | 7.3 ± 1.7 | | 6.9 ± 1.6 | |
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Note. Statistically significant. |