Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz

Figure 1

Schematic representation of efavirenz metabolism in the liver. It should be noted that the main route of efavirenz metabolism is 8-hydroxyefavirenz, which is predominately formed by CYP2B6. UGT, uridine 5′-diphospho-glucuronosyltransferase.