Identification of Important Genes of Keratoconus and Construction of the Diagnostic Model

Figure 6

Through KEGG signal pathway enrichment analysis of 686 genes significantly enriched in 6 modules, a total of 12 significantly related frontal KEGG signal pathways were obtained, as shown in Figure 6(a). Then, the quantitative analysis of 12 KEGG signal pathways with significant enrichment correlation was carried out, and 50 pairs of interconnected pairs were obtained after retaining the connection pairs with P value less than 0.05 and absolute value of correlation p value higher than 0.5, so as to construct the cross talk network of KEGG signal pathway, as shown in Figure 6(b).

(a)

(b)