Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease
Table 2
Baseline characteristics of 954 study subjects.
Group
Healthy control n = 298
Chronic HBV infection patient
-valuec
Non-HCC
HBV-related HCC
n = 370
-valuea
n = 286
-valueb
Male, n (%)
246 (82.6)
295 (79.7)
0.3734
245 (85.7)
0.3112
1.0000
Age, M (P25, P75)
50 (45,55)
49 (42,55)
0.0885
50 (46,56)
0.5214
0.4585
Smoking
0.4654
0.0023
0.2574
Ever, n (%)
112 (37.6)
128 (34.6)
144 (50.3)
Never, n (%)
186 (62.4)
242 (65.4)
142 (49.7)
Drinking
0.0416
0.8052
0.2542
Ever, n (%)
121 (40.6)
122 (33.0)
119 (41.6)
Never, n (%)
177 (59.4)
248 (67.0)
167 (58.4)
-valuea,b,c represents the non-HCC, HCC, and chronic HBV patients compared to the healthy controls. The rank-sum test or χ2 test was used to evaluate continuous numeric variables and grouping variables in demographic data among the groups. HBV, hepatitis B virus; HCC, hepatocellular carcinoma.
