Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease

Table 3

Baseline characteristic of chronic HBV infection subgroups.

	Non-HCC			HCC
	CHB n = 104	-value^a	LC n = 266	-value^b	n = 286	-value^c
Male, n (%)	84 (80.8)	0.7558	211 (79.3)	0.0495	245 (85.7)	0.0482
Age, M (P25, P75)	47 (43,53)	0.3404	49 (41,56)	0.1443	50 (46,56)	0.0220
Smoking		0.8039		0.0001		<0.0001
Ever, n (%)	37 (35.6)		91 (34.2)		144 (50.3)
Never, n (%)	67 (64.4)		175 (65.8)		142 (49.7)
Drinking		0.1217		0.1305		0.0229
Ever, n (%)	28 (26.9)		94 (35.3)		119 (41.6)
Never, n (%)	76 (73.1)		172 (64.7)		167 (58.4)

-value^a,b,c represents the CHB vs. LC, LC vs. HCC, and non-HCC vs. HCC, respectively. The rank-sum test or χ2 text was used to evaluate continuous numeric variables and grouping variables in demographic data among the groups. CHB, chronic hepatitis B; CI, confidence interval; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; LC, liver cirrhosis; OR, odds ratio.