Research Article
Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease
Table 6
Haplotype distributions between healthy controls and chronic HBV infection patients.
| | Haplotype | Frequency | χ2 | | OR (95% CI) | | Healthy controls (%) | Chronic HBV infection (%) |
| | rs3754217-rs3737240 | | G-C | 397 (67.7) | 931 (71.4) | 8.47 | 0.0373 | 1 | | G-T | 22 (3.8) | 28 (2.1) | | | 0.54 (0.31-0.96) | | T-C | 52 (8.9) | 80 (6.1) | | | 0.64 (0.44-0.93) | | T-T | 115 (19.6) | 265 (20.3) | | | 0.99 (0.77-1.27) |
| | rs3834087-rs3754217-rs3737240 | | G-G-C | 395 (67.2) | 931 (71.4) | 17.2 | 0.0086 | 1 | | G-G-T | 22 (3.7) | 28 (2.6) | | | 0.54 (0.31-0.96) | | G-T-C | 3 (0.5) | 4 (0.4) | | | 0.55 (0.12-2.49) | | G-T-T | 115 (19.6) | 259 (19.8) | | | 0.95 (0.74-1.22) | | D-G-C | 4 (0.7) | 0 (0.0) | | | — | | D-T-C | 49 (8.3) | 76 (5.8) | | | 0.65 (0.45-0.96) | | D-T-T | 0 (0.0) | 6 (0.3) | | | — |
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rs3834087’s GAG allele was simply marked with G; DEL allele was simply marked with D. CI, confidence interval; HBV, hepatitis B virus; OR, odda ratio. |
