Associations between Extracellular Matrix Protein 1 Gene Polymorphism and Progression of Liver Disease

Table 7

Haplotype distributions between healthy controls and non-HCC patients.

Haplotype	Frequency		χ^2		OR (95% CI)
	Healthy controls (%)	Non-HCC (%)
rs3834087-rs3754217
G-G	416 (70.7)	554 (75.1)	10.42	0.0153	1
G-T	119 (20.2)	144 (19.5)			0.91 (0.69-1.20)
D-G	4 (0.7)	0 (0.0)			1.00 (0.99-1.02)
D-T	49 (8.3)	40 (5.4)			0.61 (0.40-0.95)
rs3754217-rs3737240
G-C	398 (67.7)	536 (72.8)	10.42	0.0153	1
G-T	22 (3.7)	17 (2.3)			0.57 (0.29-1.11)
T-C	53 (9.0)	37 (5.0)			0.51 (0.33-0.81)
T-T	115 (19.6)	146 (19.8)			0.94 (0.72-1.25)

rs3834087’s GAG allele was simply marked with G; DEL allele was simply marked with D. CI, confidence interval; HCC, hepatocellular carcinoma; OR, odds ratio.