Genetic Variations in the Human Angiotensin-ConvertingEnzyme 2 and Susceptibility to Coronavirus Disease-19

Figure 2

(a) The image depicts the secondary structure of the angiotensin-converting enzyme 2 protein. (b) The image illustrates the dimerization structure of the ACE2 protein with SWISS-MODEL (https://swissmodel.expasy.org/) ID Q9BYF1. ACE2 dimerizes via 2 domains: peptidase-M2 and collectrin, which are shown in color. (c) The image demonstrates the crystal structure of ACE2 with PDB (https://www.rcsb.org/) ID 1R42. The main functional domains of ACE2 that interact with SARS-CoV-2 are illustrated in the box.

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