Lack of Association of C677T Methylenetetrahydrofolate Reductase Polymorphism with Breast Cancer Risk in Mali

Table 2

Distribution of C677T MTHFR polymorphism in the breast cancer group according to genetic models.

Genotype/allele	Cases	Controls	OR (95% CI)
	N = 127	N = 160
CC	112 (88.2)	145 (90.6)	Reference
CT	14 (11.0)	14 (8.8)	1.29 (0.59–2.82)	0.52
TT	1 (0.8)	1 (0.6)	1.29 (0.08–20.92)	0.85
TT + CT	15 (11.8)	15 (10.0)	1.29 (0.61–2.76)	0.50
CC + CT	126 (99.2)	159 (99.4)	Reference
TT	1 (0.8)	1 (0.6)	1.26 (0.08–20.37)	0.87
C	238 (93.7)	304 (95.0)	Reference
T	16 (6.3)	16 (5.0)	1.28 (0.62–2.61)	0.50

N= number; CI: confidence interval; : value; TT + CT vs. CC: the dominant model; TT vs. CC + CT: the recessive model; T vs. C: the additive model;