Research Article
The Clinical and Cellular Impact of RBMS2 on the Progression and Prognosis of Kidney Renal Clear Cell Carcinoma
Table 2
ccRCC overall survival analysis.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | Hazard ratio (95% CI) | value | Hazard ratio (95% CI) | value |
| Gender | 541 | | 0.614 | | | Female | 187 | Reference | | | | Male | 354 | 0.924 (0.679–1.257) | 0.613 | | | Age | 541 | | <0.001 | | | ≤60 | 269 | Reference | | Reference | | >60 | 272 | 1.791 (1.319–2.432) | <0.001 | 1.728 (1.046–2.854) | 0.033 | Serum calcium | 367 | | 0.076 | | | Low | 204 | Reference | | Reference | | Normal and elevated | 163 | 1.356 (0.969–1.899) | 0.076 | 0.622 (0.380–1.018) | 0.059 | Histologic grade | 533 | | <0.001 | | | G1 and G2 | 250 | Reference | | Reference | | G3 and G4 | 283 | 2.665 (1.898–3.743) | <0.001 | 0.985 (0.560–1.735) | 0.960 | Pathologic T stage | 541 | | <0.001 | | | T1 and T2 | 350 | Reference | | Reference | | T3 and T4 | 191 | 3.210 (2.373–4.342) | <0.001 | 2.207 (1.304–3.737) | 0.003 | Pathologic N stage | 258 | | 0.001 | | | N0 | 242 | Reference | | Reference | | N1 | 16 | 3.422 (1.817–6.446) | <0.001 | 0.829 (0.308–2.232) | 0.710 | Pathologic M stage | 508 | | <0.001 | | | M0 | 429 | Reference | | Reference | | M1 | 79 | 4.401 (3.226–6.002) | <0.001 | 5.154 (2.926–9.080) | <0.001 | RBMS2 | 541 | | <0.001 | | | Low | 270 | Reference | | Reference | | High | 271 | 0.545 (0.399–0.744) | <0.001 | 0.719 (0.436–1.184) | 0.195 |
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Bold values indicate P<0.05.
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