Research Article
The Clinical and Cellular Impact of RBMS2 on the Progression and Prognosis of Kidney Renal Clear Cell Carcinoma
Table 4
ccRCC progression-free survival.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | Hazard ratio (95% CI) | value | Hazard ratio (95% CI) | value |
| Gender | 539 | | 0.024 | | | Female | 186 | Reference | | Reference | | Male | 353 | 1.476 (1.043–2.090) | 0.028 | 1.650 (0.980–2.779) | 0.060 | Age | 539 | | 0.113 | | | ≤60 | 268 | Reference | | | | >60 | 271 | 1.285 (0.942–1.754) | 0.114 | | | Serum calcium | 366 | | 0.054 | | | Low | 203 | Reference | | Reference | | Normal and elevated | 163 | 1.422 (0.994–2.034) | 0.054 | 0.520 (0.301–0.901) | 0.020 | Histologic grade | 531 | | <0.001 | | | G1 and G2 | 250 | Reference | | Reference | | G3 and G4 | 281 | 3.684 (2.530–5.364) | <0.001 | 0.873 (0.465–1.639) | 0.672 | Pathologic T stage | 539 | | <0.001 | | | T1 and T2 | 350 | Reference | | Reference | | T3 and T4 | 189 | 4.569 (3.306–6.314) | <0.001 | 3.443 (1.923–6.167) | < 0.001 | Pathologic N stage | 257 | | 0.001 | | | N0 | 241 | Reference | | Reference | | N1 | 16 | 3.697 (1.899–7.198) | <0.001 | 0.461 (0.166–1.276) | 0.136 | Pathologic M stage | 506 | | <0.001 | | | M0 | 429 | Reference | | Reference | | M1 | 77 | 9.081 (6.554–12.582) | <0.001 | 15.996 (7.983–32.049) | < 0.001 | RBMS2 | 539 | | <0.001 | | | Low | 268 | Reference | | Reference | | High | 271 | 0.481 (0.347–0.668) | <0.001 | 0.527 (0.308–0.903) | 0.020 |
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Bold values indicate P<0.05.
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