Research Article

The Clinical Relevance and Functional Implications of Thymosin Beta-10 in Glioma

Figure 1

Correlations between TMSB10 expression and patients’ characteristics in glioma. (a) Comparison of TMSB10 expression levels between glioma tissues and normal brain tissues using data from TCGA and GTEx databases. TMSB10 expression was significantly upregulated in glioma tissues compared to normal brain tissues. (b) Box plot illustrating the association between TMSB10 expression levels and histological grades of glioma. Higher histological grades were associated with higher TMSB10 expression levels. (c) Box plot depicting the correlation between TMSB10 expression levels and patients’ age. TMSB10 expression showed a positive correlation with age in glioma patients. (d) Box plot illustrating the correlation between TMSB10 expression levels and patients’ gender. No statistically significant correlation was observed between TMSB10 expression and gender. (e) Box plot demonstrating the association between TMSB10 expression levels and IDH status in glioma patients. TMSB10 showed significantly higher expression levels in glioma patients with wild-type IDH. (f) Box plot displaying the association between TMSB10 expression levels and 1p/19q codeletion in glioma patients. TMSB10 exhibited significantly higher expression levels in glioma patients with noncodeletion of 1p/19q. Data were compared using Wilcoxon rank sum test.
(a)
(b)
(c)
(d)
(e)
(f)