The Clinical Relevance and Functional Implications of Thymosin Beta-10 in Glioma

Figure 3

In vitro and in vivo experiments to test the glioma-related function of TMSB10. (a, b) RT-qPCR assay results showing the knockdown efficiency of TMSB10 in two glioma cells (U251 and LN229). (c, d) MTT assay results showing the growth rates of TMSB10-knockdown glioma cells (U251 and LN229) compared to control groups. TMSB10-knockdown cells exhibited significantly slower growth rates. (e, f) Representative images of xenograft tumors derived from TMSB10-knockdown glioma cells and control groups. Tumors derived from TMSB10-knockdown cells showed significantly impaired growth compared to control tumors. (g, h) Bar graph illustrating the quantification of tumor volume based on xenograft experiments. Tumors derived from TMSB10-knockdown cells exhibited significantly reduced growth compared to control tumors.

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