The Clinical Relevance and Functional Implications of Thymosin Beta-10 in Glioma

Table 2

Univariate and multivariate overall survival analyses.

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Age	698
≤60 yrs	555	Reference		Reference
>60 yrs	143	4.696 (3.620–6.093)	<0.001	1.539 (1.130–2.097)	0.006
Gender	698
Female	297	Reference		Reference
Male	401	1.250 (0.979–1.595)	0.073	1.234 (0.937–1.625)	0.134
IDH status	688
WT	246	Reference		Reference
Mut	442	0.116 (0.089–0.151)	<0.001	0.342 (0.224–0.523)	<0.001
1p/19q codeletion	691
Noncodel	520	Reference		Reference
Codel	171	0.225 (0.147–0.346)	<0.001	0.768 (0.459–1.286)	0.316
WHO grade	636		<0.001
G2	223	Reference		Reference
G3	245	2.967 (1.986–4.433)	<0.001	1.741 (1.124–2.697)	0.013
G4	168	18.600 (12.448–27.794)	<0.001	4.002 (2.338–6.851)	<0.001
TMSB10	698
Low	348	Reference		Reference
High	350	6.025 (4.487–8.089)	<0.001	1.647 (1.058–2.564)	0.027