Research Article
The Clinical Relevance and Functional Implications of Thymosin Beta-10 in Glioma
Table 2
Univariate and multivariate overall survival analyses.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | Hazard ratio (95% CI) | value | Hazard ratio (95% CI) | value |
| Age | 698 | | | | | ≤60 yrs | 555 | Reference | | Reference | | >60 yrs | 143 | 4.696 (3.620–6.093) | <0.001 | 1.539 (1.130–2.097) | 0.006 | Gender | 698 | | | | | Female | 297 | Reference | | Reference | | Male | 401 | 1.250 (0.979–1.595) | 0.073 | 1.234 (0.937–1.625) | 0.134 | IDH status | 688 | | | | | WT | 246 | Reference | | Reference | | Mut | 442 | 0.116 (0.089–0.151) | <0.001 | 0.342 (0.224–0.523) | <0.001 | 1p/19q codeletion | 691 | | | | | Noncodel | 520 | Reference | | Reference | | Codel | 171 | 0.225 (0.147–0.346) | <0.001 | 0.768 (0.459–1.286) | 0.316 | WHO grade | 636 | | <0.001 | | | G2 | 223 | Reference | | Reference | | G3 | 245 | 2.967 (1.986–4.433) | <0.001 | 1.741 (1.124–2.697) | 0.013 | G4 | 168 | 18.600 (12.448–27.794) | <0.001 | 4.002 (2.338–6.851) | <0.001 | TMSB10 | 698 | | | | | Low | 348 | Reference | | Reference | | High | 350 | 6.025 (4.487–8.089) | <0.001 | 1.647 (1.058–2.564) | 0.027 |
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