Pharmacogenetic Approach for the Prevention of Rivaroxaban’s ADRs: A Systematic Review and Meta-Analysis

Table 3

Impact of rs1045642 on rivaroxaban concentrations.

Description of analysis	Pooled SMD (95% CI)	Sample size	Heterogeneity
			I^2 (%)	p value	Model
CC vs. AA	−0.516 (−0.917 to −0.115)	86	0.0	0.815	Random
AC vs. AA	−0.867 (−1.215 to −0.519)	86	69.8	0.069	Fixed

SMD, standardized mean difference; CI, confidence interval; value was reported for the heterogeneity chi-squared test. A fixed model was used whenever value was less than 0.1.