Establishment of a Lymph Node Metastasis-Associated Prognostic Signature for Lung Adenocarcinoma

Figure 5

Construction and validation of metastasis-associated signature model in the training and three validation cohorts. (a) The distribution and survival state of samples in the TCGA cohort. (b) Kaplan–Meier (KM) survival curves for samples in the high-risk (HR) and low-risk (LR) groups of TCGA cohort. (c) Receiver operating characteristic (ROC) analysis of overall survival at 1, 3, and 5 years in TCGA cohort. (d) The distribution and survival state of samples in the GSE68465. (e) KM survival curves showing survival outcomes of GSE68465. (f) ROC analysis of GSE68465. (g) Distribution of patients in GSE42127 based on the median RS and survival status for each case. (h) Overall survival curves for patients in LR and HR groups in GSE42127 dataset. (i) ROC curve showed the predictive efficiency of the RS in GSE42127. (j) RS distribution and survival status distribution of patients in GSE50081. (k) KM curves of overall survival in GSE50081. (l) ROC curves for 1-, 3-, and 5-year survival in GSE50081.

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