Allelic and Genotype Frequencies of CYP2B6^∗2 (64C > T) and CYP2B6^∗3 (777C > A) in Three Dominant Ethnicities of the Iranian Population

Table 3

Analysis of the CYP2B6^∗2 genotypic frequencies (%) among three dominant ethnicities in Iran; the correlation between ethnicity genotype frequency ethnicity and the each ethnicity is shown.

Number (%)		Ethnicity
		Fars	Turk	Kurd	Total
		80 (46%)	69 (40%)	25 (14%)	174 (100%)
CYP2B6^∗2	Wild (C/C) (95% CI)	6.3% (5.7–6.9)	10.3% (9.3–11.3)	12% (10.3–13.7)	8.7% (6.7–10.7)
	Heterozygous (C/T) (95% CI)	91.1% (87.5–94.7)	79.4% (73.5–85.5)	88% (80.2–95.8)	86% (83.2–88.8)
	Mutant (T/T) (95% CI)	2.5% (1.7–3.3)	10.3% (5.2–15.4)	0%	5.2% (3.9–6.5)
	value	<0.001	0.041	<0.001
CYP2B6^∗3	Wild (C/C) (95% CI)	74.7% (70.6–78.8)	77.8% (74.6–81)	72% (65.3–78.7)	75.3% (70.1–80.5)
	Heterozygous (C/A) (95% CI)	9.3% (7.2–11.4)	11.1% (6.6–15.6)	16% (11.8–20.2)	11% (8.3–13.7)
	Mutant (A/A) (95% CI)	16% (13.7–18.3)	11.1% (7.4–14.8)	12% (9.1–14.9)	13.6% (12.5–14.7)
	value	<0.001	<0.001	<0.001

value of less than 0.05 is statistically significant. value of less than 0.01 is statistically highly significant.