Sex-Biased Expression of Genes Allocated in the Autosomal Chromosomes: Blood LC-MS/MS Protein Profiling in Healthy Subjects

Figure 1

Histograms of the normalized abundance of differentially expressed proteins/peptides (PPs) identified in healthy males (black) and females (grey). (a) PPs upregulated in women compared with men, and (b) PPs upregulated in men compared with women. The -values (ANOVA) and magnitude of change (maximum fold change–MFC) are indicated for each PP in each figure. The proteins were identified using label-free quantified liquid chromatography-tandem mass spectrometry on Synapt G2 analysis–LC-MS/MS. Progenesis QI for proteomics software was used for data analysis. Note. There are no bar errors as samples are usually pooled in LC-MS/MS analysis.

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